Digital discovery of antimicrobial molecules from marine Artic resources with reduced risk of triggering resistance.
Antimicrobial resistance is currently causing around 700 000 deaths annually, with an estimated rise to 10 million over the next 30 years. Continuous development of antimicrobial compounds with new modes of action is essential to reduce the risk posed by antimicrobial resistance. To contribute to meeting this challenge, DigiBiotics will explore new compounds inspired by marine Arctic natural products and develop novel experimental and computational methods for determining molecular structure and dynamics. This will allow for a better understanding of peptide-membrane interactions and provide an atomic basis for the development of new drug targets. Promising compounds will be refined to compounds acceptable for industrial drug development.
24. Jan 2020
RRI Helse Cross project activities
22. Aug 2019
Forskning Helse Forskerskolen
22. Nov 2018
Jeanette Hammer Andersen
Marte Jenssen, Jeanette Hammer Andersen, Teppo Rämä, Espen Holst Hansen, Kine Østnes Hansen, Chun Li
Jeanette hammer Andersen
Espen Holst Hansen, Kine Ø. Hanssen, Jeanette hammer Andersen
Ole Christian Hagestad, Jeanette hammer Andersen, Bjørn Altermark, Espen Hansen, Teppo Rämä